FLIPR Calcium 5 Data Sheet rev B

biological signals during your screens. In addition, the FLIPR Calcium 5 Assay Kit can be used in even the most difficult assays, such as those of receptors expressed at low levels, chemokines, allosteric modulators, primary cell lines, and partial agonists. No other calcium mobilization assay on the market today will give you greater confidence in the results of your screens.

HIGHER THROUGHPUT CAPACITY

Productivity. The secret to the streamlined protocol that is the hallmark of FLIPR Calcium Assays lies in the quench technology. The

Calcium 5 Assay Kit leverages the same quench technology as the highly successful Calcium 4 Assay Kit to deliver the same streamlined

protocol. Our proven quench technology lowers the background signal from extracellular response (Figure 1), eliminating the need to wash cells or remove serum-containing media and therefore minimizing assay preparation time and protocol steps. No other similar assay on the market

today will give you greater throughput capacity.

BEsT-In-ClAss sOlUTIOn TO sUPPORT HIGH-THROUGHPUT sCREEnInG Of dIffICUlT TARGETs

flIPR Calcium 5 Assay Kit

The FLIPR ? Calcium 5 Assay Kit from

Molecular Devices enables researchers to conduct highly sensitive fluorescent screens of G-protein coupled receptors (GPCRs) and ion channels. By using the latest fluorescent indicator dye technology, the assay kit delivers superior signal-to-noise ratio compared to similar commercially available kits for enhanced performance even in difficult assays. In addition, the Calcium 5 Assay Kit leverages the proven quench technology from the FLIPR Calcium 4 Assay Kit as well as the streamlined protocol that is the hallmark of FLIPR Calcium Assays. Building on over a decade of development experience focused on no-wash calcium mobilization assays, Molecular Devices is confident that the FLIPR Calcium 5 Assay will meet, and likely exceed, your performance expectations for high throughput GPCR and ion channel screening assays.

sUPERIOR sIGnAl-TO-nOIsE RATIO

Confidence. With one of the highest—if not the highest—signal-to-noise ratio among similar commercial assays on the market today, you can be confident in your ability to detect relevant

> sUPERIOR sIGnAl-TO-nOIsE

RATIO

> HIGHER THROUGHPUT

CAPACITY

> EnHAnCEd PERfORMAnCE > MIx-And-REAd PROTOCOl > EAsIlY AUTOMATABlE

AssAY

flIPR CAlCIUM 5 AssAY KIT

sAlEs OffICEs

>

USA & Canada +1-800-635-5577> Brazil +55-11-3616-6607

> China (Beijing) +86-10-6410-8669> China (Shanghai) +86-21-6887-8820> Germany +49-89/96-05-88-0> Japan (Osaka) +81-6-6399-8211> Japan (Tokyo) +81-3-5282-5261> South Korea +82-2-3471-9531

> United Kingdom +44-118-944-8000Check our web site for a current listing of our worldwide distributors. https://www.wendangku.net/doc/0a8589042.html,

fOR REsEARCH UsE OnlY . nOT fOR UsE In dIAGnOsTIC PROCEdUREs.

The trademarks used herein are the property of Molecular devices, Inc. or their respective owners.

specifications subject to change without notice.

EnHAnCEd PERfORMAnCE, COnsIsTEnTlY Reliability. T oday’s FLIPR Calcium 5 Assay Kit benefits from more than 10 years of development know-how to deliver a truly reliable assay. Results generated with this assay kit are consistent with previously published data, so you can be assured of a seamless transition (Figure 2) to the Calcium 5 Assay. Also, the Calcium 5 Assay demonstrates consistently higher performance in relation to other similar mix-and-read assays (Figure 3), so you can achieve the best possible response.

The FLIPR Calcium 5 Assay Kit represents the latest advancements in calcium mobilization assays. This kit, like all FLIPR Assay Kits, is compatible with any FLIPR or FlexStation ? System from Molecular Devices, as well as other similar dispense-and-read systems.

T o evaluate the kit’s performance in your lab, please contact your local sales representative and let the data speak for itself.

ORdERInG InfORMATIOn

FLIPR Calcium Assay Evaluation Kit Part Number: R8172

> (3) vials Component A* of Calcium 3 Assay Kit > (3) vials Component A* of Calcium 4 Assay Kit > (3) vials Component A* of Calcium 5 Assay Kit > 1 bottle Component B

*Each reagent vial sufficient for 1 plate (96, 384, 1536)

FLIPR Calcium 5 Assay Explorer Kit Part Number: R8185

> (10) vials Component A*> (1) vial Component B

*Each reagent vial sufficient for 1 plate (96, 384, 1536)

FLIPR Calcium 5 Assay Bulk Kit Part Number: R8186

> (10) vials Component A*

*Each reagent vial sufficient for 10 plates (96, 384, 1536)

FLIPR Calcium 5 Assay Express Kit Part Number: R8187

> (2) vials Component A*

*Each reagent vial sufficient for 50 plates (96, 384, 1536)

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?2010 Molecular Molecular devices, Inc. Printed in U.s.A. 6/10 #0120-1492B