18.Isobutanol

Product Name:Issue Date:11/06/2007

Print Date:18Feb 2009*Indicates a Trademark Dow Chemical Pacific Limited encourages and expects you to read and understand the entire (M)SDS,as there is important information throughout the document.We expect you to follow the precautions identified in this document unless your use conditions would necessitate other appropriate methods or actions.1.Product and Company Identification

Product Name

COMPANY IDENTIFICATION

Dow Chemical Pacific Limited

A Subsidiary of The Dow Chemical Company

47/F.Sun Hung Kai Centre,

30Harbour Road

Wanchai,HK

-?′?

Customer Information Number:(603)79583392

EMERGENCY TELEPHONE NUMBER

24-Hour Emergency Contact:

(852)24313300Local Emergency Contact:989-636-4400

2.Hazards Identification

Emergency Overview

Color:Colorless

Physical State:Liquid

Odor:Mild Hazards of product:

WARNING!Causes eye irritation.Causes skin irritation.Flammable liquid and vapor.Harmful if inhaled.Static ignition hazard can result from handling and use.May cause central nervous system effects.May cause anesthetic effects.

Aspiration hazard.Can enter lungs and cause damage.

OSHA Hazard Communication Standard

This product is a "Hazardous Chemical"as defined by the OSHA Hazard Communication Standard,29CFR 1910.1200.

Potential Health Effects

Eye Contact:May cause severe eye irritation.May cause moderate corneal injury.

Material Safety Data Sheet

Dow Chemical Pacific Limited

Skin Contact:Brief contact may cause moderate skin irritation with local redness.May cause drying and flaking of the skin.May cause more severe response on covered skin(under clothing,gloves). Skin Absorption:Prolonged skin contact is unlikely to result in absorption of harmful amounts.In animals,effects have been reported on the following organs after dermal exposure:Central nervous system.

Inhalation:Prolonged excessive exposure may cause adverse effects.Symptoms of excessive exposure may be anesthetic or narcotic effects;dizziness and drowsiness may be observed.May cause central nervous system effects.

Ingestion:Low toxicity if swallowed.Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury;however,swallowing larger amounts may cause injury.May cause central nervous system depression.Aspiration into the lungs may occur during ingestion or vomiting,causing lung damage or even death due to chemical pneumonia.

Effects of Repeated Exposure:In animals,effects have been reported on the following organs: Liver.Central nervous system.Observations in animals include:Anesthetic or narcotic effects.

https://www.wendangku.net/doc/302400368.html,position Information

Component CAS#Amount Isobutanol78-83-1<=100.0%

4.First-aid measures

Eye Contact:Immediately flush eyes with water;remove contact lenses,if present,after the first5 minutes,then continue flushing eyes for at least15minutes.Obtain medical attention without delay, preferably from an ophthalmologist.

Skin Contact:Wash skin with plenty of water.

Inhalation:Move person to fresh air.If not breathing,give artificial respiration;if by mouth to mouth use rescuer protection(pocket mask,etc).If breathing is difficult,oxygen should be administered by qualified personnel.Call a physician or transport to a medical facility.

Ingestion:Do not induce vomiting.Call a physician and/or transport to emergency facility immediately. Notes to Physician:If lavage is performed,suggest endotracheal and/or esophageal control.Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach.The decision of whether to induce vomiting or not should be made by a physician.Maintain adequate ventilation and oxygenation of the patient.No specific antidote.Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.

5.Fire Fighting Measures

Extinguishing Media:Water fog or fine spray.Dry chemical fire extinguishers.Carbon dioxide fire extinguishers.Foam.Do not use direct water stream.Straight or direct water streams may not be effective to extinguish fire.Alcohol resistant foams(ATC type)are preferred.General purpose synthetic foams(including AFFF)or protein foams may function,but will be less effective.

Fire Fighting Procedures:Keep people away.Isolate fire and deny unnecessary entry.Stay upwind.Keep out of low areas where gases(fumes)can accumulate.Water may not be effective in extinguishing https://www.wendangku.net/doc/302400368.html,e water spray to cool fire exposed containers and fire affected zone until fire is out and danger of reignition has passed.Do not use direct water stream.May spread fire.Eliminate ignition sources.Move container from fire area if this is possible without hazard.Burning liquids may be moved by flushing with water to protect personnel and minimize property damage.Avoid accumulation of water.Product may be carried across water surface spreading fire or contacting an ignition source.

Special Protective Equipment for Firefighters:Wear positive-pressure self-contained breathing apparatus(SCBA)and protective fire fighting clothing(includes fire fighting helmet,coat,trousers, boots,and gloves).If protective equipment is not available or not used,fight fire from a protected location or safe distance.

Unusual Fire and Explosion Hazards:Violent steam generation or eruption may occur upon application of direct water stream to hot liquids.When product is stored in closed containers,a flammable atmosphere can develop.Electrically ground and bond all equipment.Flammable mixtures of this product are readily ignited even by static discharge.Vapors are heavier than air and may travel a long distance and accumulate in low lying areas.Ignition and/or flash back may occur.Flammable mixtures may exist within the vapor space of containers at room temperature.Flammable concentrations of vapor can accumulate at temperatures above flash point;see Section9. Hazardous Combustion Products:During a fire,smoke may contain the original material in addition to combustion products of varying composition which may be toxic and/or https://www.wendangku.net/doc/302400368.html,bustion products may include and are not limited to:Carbon monoxide.Carbon dioxide.

6.Accidental Release Measures

Steps to be Taken if Material is Released or Spilled:Contain spilled material if possible.Ground and bond all containers and handling equipment.Collect in suitable and properly labeled containers. Pump with explosion-proof equipment.If available,use foam to smother or suppress.See Section13, Disposal Considerations,for additional information.

Personal Precautions:Use appropriate safety equipment.For additional information,refer to Section 8,Exposure Controls and Personal Protection.Isolate area.Refer to Section7,Handling,for additional precautionary measures.Keep unnecessary and unprotected personnel from entering the area.Keep personnel out of low areas.Keep upwind of spill.Ventilate area of leak or spill.No smoking in area.Eliminate all sources of ignition in vicinity of spill or released vapor to avoid fire or explosion.For large spills,warn public of downwind explosion hazard.Check area with combustible gas detector before reentering area.Ground and bond all containers and handling equipment.Vapor explosion hazard.Keep out of sewers.

Environmental Precautions:Prevent from entering into soil,ditches,sewers,waterways and/or groundwater.See Section12,Ecological Information.

7.Handling and Storage

Handling

General Handling:Avoid contact with eyes,skin,and clothing.Keep away from heat,sparks and flame.Avoid breathing vapor.Do not swallow.Keep container https://www.wendangku.net/doc/302400368.html,e with adequate ventilation.Wash thoroughly after handling.No smoking,open flames or sources of ignition in handling and storage area.Ignition sources can include and are not limited to pilot lights,flames, smoking,sparks,heaters,electrical equipment,and static discharges.Electrically bond and ground all containers,personnel and equipment before transfer or use of material.Never use air pressure for transferring https://www.wendangku.net/doc/302400368.html,e of non-sparking or explosion-proof equipment may be necessary,depending upon the type of operation.Containers,even those that have been emptied,can contain vapors.Do not cut,drill,grind,weld,or perform similar operations on or near empty containers.

Other Precautions:Vapors are heavier than air and may travel a long distance and accumulate in low lying areas.Ignition and/or flash back may occur.

Storage

Store in a dry place.Store away from direct sunlight.Store in original container.Minimize sources of ignition,such as static build-up,heat,spark or flame.Keep container closed.

8.Exposure Controls/Personal Protection

Exposure Limits

Component List Type Value

Isobutanol ACGIH TWA50ppm

OSHA Table

PEL300mg/m3100ppm

Z-1

Personal Protection

Eye/Face Protection:Use chemical goggles.

Skin Protection:Use protective clothing chemically resistant to this material.Selection of specific items such as face shield,boots,apron,or full body suit will depend on the task.Remove contaminated clothing immediately,wash skin area with soap and water,and launder clothing before reuse or dispose of properly.

Hand protection:Use gloves chemically resistant to this material.Examples of preferred

glove barrier materials include:Viton.Butyl rubber.Polyethylene.Neoprene.Chlorinated

polyethylene.Natural rubber("latex").Polyvinyl chloride("PVC"or"vinyl").Ethyl vinyl alcohol laminate("EVAL").Examples of acceptable glove barrier materials include:Nitrile/butadiene rubber("nitrile"or"NBR").NOTICE:The selection of a specific glove for a particular

application and duration of use in a workplace should also take into account all relevant

workplace factors such as,but not limited to:Other chemicals which may be handled,physical requirements(cut/puncture protection,dexterity,thermal protection),potential body reactions to glove materials,as well as the instructions/specifications provided by the glove supplier. Respiratory Protection:Atmospheric levels should be maintained below the exposure guideline. When respiratory protection is required,use an approved air-purifying or positive-pressure supplied-air respirator depending on the potential airborne concentration.For emergency and other conditions where the exposure guideline may be exceeded,use an approved positive-pressure self-contained breathing apparatus or positive-pressure air line with auxiliary self-contained air supply.The following should be effective types of air-purifying respirators:Organic vapor cartridge.

Ingestion:Avoid ingestion of even very small amounts;do not consume or store food or tobacco in the work area;wash hands and face before smoking or eating.

Engineering Controls

Ventilation:Provide general and/or local exhaust ventilation to control airborne levels below the exposure guidelines.

9.Physical and Chemical Properties

Physical State Liquid

Color Colorless

Odor Mild

Flash Point-Closed Cup28°C(82°F)ASTM D56

Flash Point-Open Cup35°C(95°F)ASTM D1310

Flammable Limits In Air Lower:1.7%(V)

Upper:10.6%(V)

Autoignition Temperature No test data available

Vapor Pressure7.2mmHg@20°C Literature

Boiling Point(760mmHg)108°C(226°F)Literature.

Vapor Density(air=1) 2.55

Specific Gravity(H2O=1)0.80220°C/20°C

Freezing Point-108°C(-162°F)Literature

Melting Point No test data available

Solubility in Water(by

10%@25°C

weight)

pH No test data available

Molecular Weight74.12g/mol

0.76Measured

Octanol/Water Partition

Coefficient

Evaporation Rate(Butyl

0.74Literature

Acetate=1)

Dynamic Viscosity 4.0mPa.s@20°C Calculated

10.Stability and Reactivity

Stability/Instability

Thermally stable at typical use temperatures.

Conditions to Avoid:Exposure to elevated temperatures can cause product to decompose.Avoid static discharge.

Incompatible Materials:Avoid contact with oxidizing materials.

Hazardous Polymerization

Will not occur.

Thermal Decomposition

Decomposition products depend upon temperature,air supply and the presence of other materials.

11.Toxicological Information

Acute Toxicity

Ingestion

LD50,Rat,male and female2,460-6,200mg/kg

Skin Absorption

LD50,Rabbit>2,000mg/kg

Inhalation

LC50,4h,Rat>8,000ppm

Repeated Dose Toxicity

In animals,effects have been reported on the following organs:Liver.Central nervous system. Observations in animals include:Anesthetic or narcotic effects.

Chronic Toxicity and Carcinogenicity

Available data are inadequate to evaluate carcinogenicity.

Developmental Toxicity

Did not cause birth defects or other effects in the fetus even at doses which caused toxic effects in the mother.

Reproductive Toxicity

In animal studies,did not interfere with reproduction.

Genetic Toxicology

In vitro genetic toxicity studies were predominantly negative.Animal genetic toxicity studies were negative.

12.Ecological Information

CHEMICAL FATE

Movement&Partitioning

Bioconcentration potential is low(BCF less than100or log Pow less than3).Potential for mobility in soil is very high(Koc between0and50).

Henry's Law Constant(H):9.78E-6atm*m3/mole;25°C Measured

Partition coefficient,n-octanol/water(log Pow):0.76Measured

Partition coefficient,soil organic carbon/water(Koc):2-72Estimated

Bioconcentration Factor(BCF):2

Distribution in Environment:Mackay Level1Fugacity Model:

Air Water.Biota Soil Sediment 31%66% 1.5% 1.4%

Persistence and Degradability

Material is readily biodegradable.Passes OECD test(s)for ready biodegradability.

Indirect Photodegradation with OH Radicals

Rate Constant Atmospheric Half-life Method

6.88E-12cm3/s 1.55d Estimated

OECD Biodegradation Tests:

Biodegradation Exposure Time Method

90%14d OECD301C Test

Biological oxygen demand(BOD):

BOD5BOD10BOD20BOD28

64-69%73-79%72-81%

Chemical Oxygen Demand:2.29mg/mg

Theoretical Oxygen Demand:2.59mg/mg

ECOTOXICITY

Material is practically non-toxic to aquatic organisms on an acute basis(LC50/EC50>100mg/L in the most sensitive species tested).

Fish Acute&Prolonged Toxicity

LC50,fathead minnow(Pimephales promelas),flow-through,96h:1,430mg/l

LC50,bluegill(Lepomis macrochirus),flow-through,96h:1,600mg/l

LC50,sheepshead minnow(Cyprinodon variegatus),static,24h:130mg/l

Aquatic Invertebrate Acute Toxicity

EC50,water flea Daphnia magna,static,48h,immobilization:1,300mg/l

EC50,water flea Daphnia pulex,static,48h,immobilization:1,100mg/l

Aquatic Plant Toxicity

EC50,green alga Selenastrum capricornutum,Growth inhibition(cell density reduction),72h:593

mg/l

Toxicity to Micro-organisms

EC50;bacteria,Growth inhibition,16h:3,000mg/l

13.Disposal Considerations

DO NOT DUMP INTO ANY SEWERS,ON THE GROUND,OR INTO ANY BODY OF WATER.All disposal practices must be in compliance with all Federal,State/Provincial and local laws and regulations.Regulations may vary in different locations.Waste characterizations and compliance with applicable laws are the responsibility solely of the waste generator.DOW HAS NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF PARTIES HANDLING OR USING THIS MATERIAL.THE INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION AS DESCRIBED IN MSDS SECTION: Composition Information.FOR UNUSED&UNCONTAMINATED PRODUCT,the preferred options include sending to a licensed,permitted:Incinerator or other thermal destruction device.As a service to its customers,Dow can provide names of information resources to help identify waste management companies and other facilities which recycle,reprocess or manage chemicals or plastics,and that manage used drums.Telephone Dow's Customer Information Group at1-800-258-2436or1-989-832-1556(U.S.),or1-800-331-6451(Canada)for further details.

14.Transport Information

DOT Non-Bulk

Proper Shipping Name:ISOBUTANOL

Technical Name:ISOBUTYL ALCOHOL

Hazard Class:3ID Number:UN1212Packing Group:PG III

DOT Bulk

Proper Shipping Name:ISOBUTANOL

Technical Name:ISOBUTYL ALCOHOL

Hazard Class:3ID Number:UN1212Packing Group:PG III

IMDG

Proper Shipping Name:ISOBUTANOL

Hazard Class:3ID Number:UN1212Packing Group:PG III

EMS Number:F-E,S-D

Marine pollutant.:No

ICAO/IATA

Proper Shipping Name:ISOBUTANOL

Hazard Class:3ID Number:UN1212Packing Group:PG III

Cargo Packing Instruction:310

Passenger Packing Instruction:309

Additional Information

Reportable quantity:5,000lb–ISOBUTYL ALCOHOL

This information is not intended to convey all specific regulatory or operational

requirements/information relating to this product.Additional transportation system information can be obtained through an authorized sales or customer service representative.It is the responsibility of the transporting organization to follow all applicable laws,regulations and rules relating to the transportation of the material.

15.Regulatory Information

OSHA Hazard Communication Standard

This product is a"Hazardous Chemical"as defined by the OSHA Hazard Communication Standard,29 CFR1910.1200.

Superfund Amendments and Reauthorization Act of1986Title III(Emergency Planning and Community Right-to-Know Act of1986)Sections311and312

Immediate(Acute)Health Hazard Yes

Delayed(Chronic)Health Hazard Yes

Fire Hazard Yes

Reactive Hazard No

Sudden Release of Pressure Hazard No

Superfund Amendments and Reauthorization Act of1986Title III(Emergency Planning and Community Right-to-Know Act of1986)Section313

To the best of our knowledge,this product does not contain chemicals at levels which require reporting under this statute.

Pennsylvania(Worker and Community Right-To-Know Act):Pennsylvania Hazardous Substances List and/or Pennsylvania Environmental Hazardous Substance List:

The following product components are cited in the Pennsylvania Hazardous Substance List and/or the Pennsylvania Environmental Substance List,and are present at levels which require reporting.

Component CAS#Amount

Isobutanol78-83-1<=100.0%

Pennsylvania(Worker and Community Right-To-Know Act):Pennsylvania Special Hazardous Substances List:

To the best of our knowledge,this product does not contain chemicals at levels which require reporting under this statute.

Comprehensive Environmental Response,Compensation,and Liability Act of1980(CERCLA) Section103

This product contains the following substances which are subject to CERCLA Section103reporting requirements and which are listed in40CFR302.4.

Component CAS#Amount

Isobutanol78-83-1<=100.0%

Butanol71-36-3<=0.1%

US.EPA Emergency Planning and Community Right-To-Know Act(EPCRA)SARA Title III Section302Extremely Hazardous Substance(40CFR355,Appendix A)

To the best of our knowledge,this product does not contain chemicals at levels which require reporting under this statute.

California Proposition65(Safe Drinking Water and Toxic Enforcement Act of1986)

This product contains no listed substances known to the State of California to cause cancer,birth defects or other reproductive harm,at levels which would require a warning under the statute.

US.Toxic Substances Control Act

All components of this product are on the TSCA Inventory or are exempt from TSCA Inventory requirements.

European Inventory of Existing Commercial Chemical Substances(EINECS)

The components of this product are on the EINECS inventory or are exempt from inventory requirements.

CEPA-Domestic Substances List(DSL)

All substances contained in this product are listed on the Canadian Domestic Substances List(DSL)or are not required to be listed.

16.Other Information

Product Literature

Additional information on this product may be obtained by calling your Dow Chemical Company sales or customer service contact.Ask for a product brochure.

Hazard Rating System

NFPA Health Fire Reactivity

130

Recommended Uses and Restrictions

Industrial solvent.Chemical intermediate.

Revision

Identification Number:1163/4085/Issue Date11/06/2007/Version: 2.0

Most recent revision(s)are noted by the bold,double bars in left-hand margin throughout this document.

Legend

N/A Not available

W/W Weight/Weight

OEL Occupational Exposure Limit

STEL Short Term Exposure Limit

TWA Time Weighted Average

ACGIH American Conference of Governmental Industrial Hygienists,Inc.

DOW IHG Dow Industrial Hygiene Guideline

WEEL Workplace Environmental Exposure Level

HAZ_DES Hazard Designation

Action Level A value set by OSHA that is lower than the PEL which will trigger the need for activities such as exposure monitoring and medical surveillance if exceeded.

Dow Chemical Pacific Limited urges each customer or recipient of this(M)SDS to study it carefully and consult appropriate expertise,as necessary or appropriate,to become aware of and understand the data contained in this(M)SDS and any hazards associated with the product.The information herein is provided in good faith and believed to be accurate as of the effective date shown above.

However,no warranty,express or implied,is given.Regulatory requirements are subject to change and may differ between various locations.It is the buyer's/user's responsibility to ensure that his activities comply with all federal,state,provincial or local laws.The information presented here pertains only to the product as shipped.Since conditions for use of the product are not under the control of the manufacturer,it is the buyer's/user's duty to determine the conditions necessary for the safe use of this product.Due to the proliferation of sources for information such as manufacturer-specific(M)SDSs,we are not and cannot be responsible for(M)SDSs obtained from any source other than ourselves.If you have obtained an(M)SDS from another source or if you are not sure that the (M)SDS you have is current,please contact us for the most current version.