视频喉镜下声门旁间隙脂肪注射治疗单侧声带麻痹的疗效观察

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视频喉镜下声门旁间隙脂肪注射治疗单侧声带麻痹的疗效观察

作者：刘遗斌张克辉游龙贵王富华罗冬罗良

来源：《中国医学创新》2017年第28期

【摘要】目的：通过对抽脂术、块状脂肪切取和脂肪颗粒切取三种不同自体脂肪获取方

法下视频喉镜下声门旁间隙脂肪注射治疗单侧声带麻痹的远近期疗效观察，初步探讨最佳的脂肪获取方法。方法：选取单侧声带麻痹患者45例，根据脂肪获取方法的不同将所有患者分为A、B、C组，每组各15例，A组经抽脂术获取脂肪，B组经块状脂肪切取获取脂肪，C组以脂肪颗粒切取获取脂肪，观察各组患者手术前后患侧声带及健侧声带上表面面积变化、各组患者术前后术后各时间嗓音分析。结果：所有患者患侧声带内注射脂肪后体积显著增加，患者患侧声带大小术后即刻显著高于术前（P

【关键词】视频喉镜；声门旁间隙脂肪注射；单侧声带麻痹；疗效

【Abstract】 Objective：To liposuction， massive fat cut and fat particles cut from three different methods to obtain autologous fat video laryngoscope subglottic space fat injection for unilateral vocal cord paralysis and long term efficacy of observation，explore the best method to get fat.Method：45 cases with unilateral vocal cord paralysis，according to the different fat acquisition method all patients were divided into A，B，and C group，15 cases in each group.A group was given liposuction，B group with massive fat cut，C group was given fat particles.The surface area of the vocal voice on patients postoperative side and contralateral vocal with patients before and after operation in each group were compared.Result：All patients with ipsilateral vocal cord injection after fat volume increased significantly，the immediate postoperative patients with vocal cord size was significantly higher than that before operation（P

【Key words】 Video laryngoscope； Subglottic fat injection； Unilateral vocal cord paralysis； Efficacy

First-author’s address：Ganzhou People’s Hospital，Ganzhou 341000，China

doi：10.3969/j.issn.1674-4985.2017.28.004

单侧声带麻痹导致的声门闭合不良是临床常见病[1]，临床表现为发声及吞咽障碍，严重

影响生活质量[2]。文献[3]报道声带脂肪注射治疗单侧声带麻痹获得良好效果，但脂肪吸收率影响远期疗效[4]，有观点认为抽脂术会破坏脂肪细胞完整性，影响其存活率[5]，相反观点则认为获取方法的不同不会影响脂肪存活率[6-7]，也有观点认为抽脂术可以提高脂肪组织生存能