Responses from two ifring patterns in inferior colliculus neurons to stimulation of the la

Responses from two ifring patterns in inferior

colliculus neurons to stimulation of the lateral

lemniscus dorsal nucleus

Xiao-ting Li;Ning-yu Wang;Yan-jun Wang;Zhi-qing Xu;Jin-feng Liu;Yun-fei Bai;Jin-sheng Dai;Jing-yi Zhao

【期刊名称】《中国神经再生研究（英文版）》

【年(卷),期】2016(011)005

【摘要】Theγ-aminobutyric acid neurons (GABAergic neurons) in the inferior colliculus are classiifed into various patterns based on their intrin-sic electrical properties to a constant current injection. Although this classiifcation is associated with physiological function, the exact role for neurons with various ifring patterns in acoustic processing remains poorly understood. In the present study, we analyzed characteristics of inferior colliculus neuronsin vitro, and recorded responses to stimulation of the dorsal nucleus of the lateral lemniscus using the whole-cell patch clamp technique. Seven inferior colliculus neurons were tested and were classiifed into two ifring patterns: sustained-regular (n = 4) and sustained-adapting ifring patterns (n = 3). The majority of inferior colliculus neurons exhibited slight changes in response to stimulation and bicuculline. The responses of one neuron with a sustained-adapting ifring pattern were suppressed after stimulation, but recovered to normal levels following application of