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EXPRESSION AND CLINICAL SIGNIFICANCE OF CD44 IN THEPERIPHERAL BLOOD OF PATIENTS WITH CASTRIC CANCER

EXPRESSION AND CLINICAL SIGNIFICANCE OF CD44 IN THEPERIPHERAL BLOOD OF PATIENTS

WITH CASTRIC CANCER

佚名

【期刊名称】《《中国癌症研究(英文版)》》

【年(卷),期】2001(013)003

【摘要】Objective: To investigate the clinical significance of cell adhesive molecule (CD44) expression on periphery blood (PB) of patients with gastric cancer. Methods: Both the level of CD44 and the immunocyte phenotype of the lymphocytes of 110 patients with gastric cancer and 100 healthy subjects were examined by flow cytometry, and the results were analyzed pathologically and statistically. Results: The mean of the CD44% in PB of the healthy subjects was 46.14±13.4 and there were no statistic differences for their age and sex. Site of tumor growth: The significant difference (P<0.01) was present between the patients with the cardiac part (C) or body of gastric (M+C) cancer and normal individuals. The significant difference (P<0.05) was present between patients with the 3 sites involved gastric cancer and normal individuals. Type of tumor mass: The significant difference (P<0.05) was present between patients with mixed type gastric cancer and normal individuals. Size of tumor mass: The significant difference was present between the normal individuals and patients with gastric cancer > 10 cm mass

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