Naratriptan hydrochloride_143388-64-1_DataSheet_MedChemExpress

Product Name:

Naratriptan hydrochloride CAS No.:

143388-64-1Cat. No.:

HY-B0197A

Product Data Sheet

MWt:

371.93Formula:

C17H26ClN3O2S Purity :>98%

Solubility:

DMSO

y Mechanisms:Biological Activity:

Naratriptan hydrochloride is a selective 5HT1receptor subtype agonist and is a triptan drug that is

Pathways:GPCR/G protein; Target:5-HT Receptor Pathways:Neuronal Signaling; Target:5-HT Receptor Naratriptan hydrochloride is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is

used for the treatment of migraine headaches.

Target: 5-HT1 Receptor Naratriptan is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches. Naratriptan is available in 2.5 mg tablets. It is a selective 5-HT1 receptor subtype agonist. Naratriptan is used for the treatment of the acute migraine attacks and the symptoms of migraine, including severe, throbbing headaches that sometimes are accompanied by nausea and

sensitivity to sound or light.The causes of migraine are not clearly understood; however, the efficacy of naratriptans and other References:

[1]. Connor HE, et al. Naratriptan: biological profile in animal models relevant to migraine.

Cephalalgia. 1997 May;17(3):145-52.g y ;,y p

triptans is believed to be due to their activity as 5HT (serotonin) agonists.A meta-analysis of 53clinical trials has shown that all triptans are effective for treating migraine at marketed d...Caution: Not fully tested. For research purposes only

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