多囊卵巢综合征患者的糖脂代谢特点分析
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多囊卵巢综合征患者的糖脂代谢特点分析
作者：李霞彭璇段娟雷美云
来源：《中国现代医生》2016年第12期
[摘要] 目的探讨多囊卵巢综合征（polycystic ovary syndrome ， PCOS）患者生殖内分泌及糖脂代谢特点。方法选择2014年10月～2015年10月在我院就诊的PCOS 患者48例，月经周期规律的输卵管因素不孕者36例作为对照组，经期抽血检测血清性激素、血糖、血脂水平，并分层分析两组肥胖与非肥胖者的糖脂代谢指标。分别比较两组糖、脂代谢指标及激素水平的差异。结果 PCOS组LH、AND、FAI、FIN、HOMA-IR、TG、TC、LDL-C水平显著高于对照组（P0.05）。PCOS组肥胖者FAI、FIN、HOMA-IR、TG、TC、LDL-C显著高于非肥胖者（P0.05）。对照组肥胖者与非肥胖者比较，FIN、HOMA-IR、TG、TC、LDL-C显著高于非肥胖者（P0.05）；其他指标差异无统计学意义（P>0.05）。结论 PCOS患者具有糖脂代谢异常特征，肥胖是糖脂代谢异常的独立因素，减轻体重，预防心血管疾病值得关注。
[关键词] 多囊卵巢综合征；糖脂代谢；性激素结合球蛋白；肥胖
[中图分类号] R287 [文献标识码] A [文章编号] 1673-9701（2016）12-0017-05
Analysis on glycolipid metabolism features in patients with polycystic ovarian syndrome
LI Xia PENG Xuan DUAN Juan LEI Meiyun
Department of Assisted Reproduction， Jiujiang Maternal and Child Care Service Centre in Jiangxi Province， Jiujiang 332000，China
[Abstract] Objective To discuss the features of reproductive endocrinology and glycolipid metabolism in patients with polycystic ovarian syndrome（PCOS）. Methods 48 PCOS patients treated in our hospital from October 2014 to October 2015 were selected， and another 36 infertile patients due to tubal factors with regular menstrual cycle were selected as control group. The levels of serum sex hormone， blood glucose， and blood lipid were tested during menstrual period， and the glycolipid metabolism indexes of obese and non-obese patients in two groups were stratified and analyzed. The differences of glycolipid metabolism indexes and levels of sex hormones were compared between two groups. Results The levels of LH， AND， FAI， FIN， HOMA-IR， TG，TC， and LDL-C were significantly lower in the PCOS group than in the control group （P0.05）.In the PCOS group， the levels of FAI， FIN， HOMA-IR， TG， TC， and LDL-C were significantly higher in obese patients than in non-obese patients（P0.05）.In the control group， the levels of FIN， HOMA-IR， TG， TC， and LDL-C were significantly higher in obese patients than in non-obese patients（P0.05）. The other indexes showed no significant difference（P>0.05）. Conclusion The glycolipid metabolism shows abnormal features in PCOS patients and obesity is a