2013雅思阅读模拟试题与答案解析

Sleep medication linked to bizarre behaviour

New evidence has linked a commonly prescribed sleep medication with bizarre behaviours， including a case in which a woman painted her front door in her sleep.

UK and Australian health agencies have released information about 240 cases of odd occurrences， including sleepwalking， amnesia and hallucinations among people taking the drug zolpidem.

While doctors say that zolpidem can offer much-needed relief for people with sleep disorders， they caution that these newly reported cases should prompt a closer look at its possible side effects.

Zolpidem， sold under the brand names Ambien， Stilnoct and Stilnox， is widely prescribed to treat insomnia and other disorders such as sleep apnea. Various forms of the drug， made by French pharmaceutical giant Sanofi-Aventis， were prescribed 674，500 times in 2005 in the UK.

A newly published report from Australia’s Federal Health Department describes 104 cases of hallucinations and 62 cases of amnesia experienced by people taking zolpidem since marketing of the drug began there in 2000. The health department report also mentioned 16 cases of strangesleepwalking by people taking the medication.

Midnight snack

In one of these sleepwalking cases a patient woke with a paintbrush in her hand after painting the front door to her house. Another case involved a woman who gained 23 kilograms over seven months while taking zolpidem. “It was only when she was discovered in front of an open refrigerator while asleep that the problem was resolved，” according to the report.

The UK’s Medicines and Healthcare products Regulatory Agency， meanwhile，has recorded 68 cases of adverse reactions to zolpidem from 2001 to 2005.

The newly reported cases in the UK and Australia add to a growing list of bizarre sleepwalking episodes linked to the drug in other countries， including reports of people sleep-driving while on the medication. In one case， a transatlantic flight had to be diverted after a passenger caused havoc after taking zolpidem.

Hypnotic effects

There is no biological pathway that has been proven to connect zolpidem with these behaviours. The drug is a benzodiazepine-like hypnotic that promotes deep sleep by interacting with brain receptors for a chemical called gamma-aminobutyric acid. While parts of the brain become less active during deep sleep， the body can still move， making sleepwalking a possibility.

The product information for prescribers advises that psychiatric adverse effects， including hallucinations， sleepwalking and nightmares， are more likely in the elderly， and treatment should be stopped if they occur.

Patient advocacy groups say they would like government health agencies and drug companies to take a closer look at the possible risks associated with sleep medicines. They stress that strange sleepwalking and sleep-driving behaviours can have risky consequences.

“When people do something in which they’re not in full control it’s always a danger，” says Vera Sharav of the New York-based Alliance for Human Research Protection， a US network that advocates responsible and ethical medical research practices.

Tried and tested

“The more reports that come out about the potential side effects of the drug，the more research needs to be done to understand if these are real side effects，” says sleep researcher Kenneth Wright at the University of Colorado in Boulder，US.

Millions of people have taken the drug without experiencing any strange side

effects， points out Richard Millman at Brown Medical School， director of the Sleep Disorders Center of Lifespan Hospitals in Providence， Rhode Island， US. He says that unlike older types of sleep medications， zolpidem does not carry as great a risk of addiction.

And Wright notes that some of the reports of “sleep-driving” linke d to zolpidem can be easily explained： some patients have wrongly taken the drug right before leaving work in hopes that the medicine will kick in by the time they reach home. Doctors stress that the medication should be taken just before going to bed.

The US Food & Drug Administration says it is continuing to "actively investigate" and collect information about cases linking zolpidem to unusual side effects.

The Ambien label currently lists strange behaviour as a “special concern” for people taking the drug. “It’s a possible rare adverse event，” says Sanofi-Aventis spokesperson Melissa Feltmann， adding that the strange sleepwalking behaviours “may not necessarily be caused by the drug” but instead result from an underlying disorder. She says that “the s afety profile [of zolpidem] is well established”. The drug received approval in the US in 1993.

Questions 1-6 Do the following statements agree with the information given in the reading passage？

In boxes 1-6 on your answer sheet write

TRUE if the statement is true according to the passage

FALSE if the statement is false according to the passage

NOT GIVEN if the information is not given in the passage

1. Ambien， Stilnoct and Stilnox are brand names of one same drug treating insomnia.

2. The wo man’s obesity problem wasn’t resolved until she stopped taking zolpidem.

3. Zolpidem received approval in the UK in 2001.

4. The bizarre behaviour of a passenger after taking zolpidem resulted in the diversion of a flight bound for the other side of the Atlantic.

5. Zolpidem is the only sleep medication that doesn’t cause addiction.

6. The sleep-driving occurrence resulted from the wrong use of zolpidem by an office worker.

Question 7-9 Choose the appropriate letters A-D and Write them in boxes 7-9 on your answer sheet.

7. How many cases of bizarre behaviours are described in an official report from Australia？

A. 68

B. 104

C. 182

D. 240

8. Which of the following is NOT mentioned in the product information about zolpidem？

A. Treatment should be stopped if side effects occur.

B. Medication should be taken just before going to bed.

C. Adverse effects are more likely in the elderly.

D. Side effects include nightmares， hallucinations and sleepwalking.

9. Who claimed that the safety description of zolpidem was well established？

A. Kenneth Wright

B. Melissa Feltmann

C. Richard Millman

D. Vera Sharav

Questions 10-13 Answer the following questions with NO MORE THAN THREE WORDS each in boxes 10-13.

10. How many times was French-made zolpidem prescribed in 2005 in Britain？

11. What kind of hypnotic is zolpidem as a drug which promotes deep sleep in patients？

12. What can sleepwalking and sleep-driving behaviours cause according to patient advocacy groups？

13. What US administration says that it has been investigating the cases relating zolpidem to unusual side effects？

Answer keys and explanations：

1. True

See para.3 from the beginning： Zolpidem， sold under the brand names Ambien，Stilnoct and Stilnox， is widely prescribed to treat insomnia and other disorders such as sleep apnea.

2. False

See para.1 under the subtitle “Midnight snack”： Another case involved a woman who gained 23 kilograms over seven months while taking zolpidem. “It was only when she was discovered in front of an open refrigerator while asleep that the problem was resolved”…

3. Not Given

See para.2 under the subtitle “Midnight snack”：The UK’s Medicines and Healthcare products Regulatory Agency， meanwhile， has recorded 68 cases of adverse reactions to zolpidem from 2001 to 2005. (The time the drug was approved in the UK was not mentioned.)

4. True

See para.3 under the subtitle “Midnight snack”： In one case， a transatlantic flight had to be diverted after a passenger caused havoc after taking zolpidem.

5. False

See para.2 under the subtitle “Tried and tested”： He says that unlike older types of sleep medications， zolpidem does not carry as great a risk of addiction.

6. Not Given

See para.3 under the subtitle “Tried and tested”： And Wright notes that some of the reports of “sleep-driving” linked to zolpidem can be easily explained：some patients have wrongly taken the drug right before leaving work in hopes that the medicine will kick in by the time they reach home. (No patients as office workers are mentioned in the passage.)

7. C

See para.4 from the beginning： A newly published report from Australia’s Federal Health Department describes 104 cases of hallucinations and 62 cases of amnesia experienced by people taking zolpidem since marketing of the drug began there in 2000. The health department report also mentioned 16 cases of strange sleepwalking by people taking the medication.

8. B

See the sentence in para.2 under the subtitle “Hypnotic effects” (The product

information for prescribers advises that psychiatric adverse effects， including hallucinations， sleepwalking and nightmares， are more likely in the elderly，and treatment should be stopped if they occur.) and the sentence in para.3 under the subtitle “Tried and tested” (Doctors “not the product information” stress that the medication should be taken just before going to bed.)

9. B

See para.5 under the subtitle “Tried and tested”： Sanofi-Aventis spokesperson Melissa Feltmann … says that “the safety profile [of zolpidem] is well established”.

10. 674，500 (times)

See para.3 from the beginning： Various forms of the drug， made by French pharmaceutical giant Sanofi-Aventis， were prescribed 674，500 times in 2005 in the UK.

11. (a) benzodiazepine-like (hypnotic)

See para.1 under the subtitle “Hypnotic effects”： The drug is a benzodiazepine-like hypnotic (类苯二氮催眠药)that promotes deep sleep by interacting with brain receptors for a chemical called gamma-aminobutyric acid.

12. risky consequences

See para.3 under the subtit le “Hypnotic effects”：Patient advocacy groups … stress that strange sleepwalking and sleep-driving behaviours can have risky consequences.

13. Food & Drug (Administration)

See para.4 under the subtitle “Tried and tested”： The US Food & Drug Administration says it is continuing to "actively investigate" and collect information about cases linking zolpidem to unusual side effects.

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2014年雅思阅读模拟试题及答案解析（2）

Next Year Marks the EU's 50th Anniversary of the Treaty A. After a period of introversion and stunned self-disbelief， continental European governments will recover their enthusiasm for pan-European institution-building in 2007. Whether the European public will welcome a return to what voters in two countries had rejected so short a time before is another matter. B. There are several reasons for Europe’s recovering self-confidence. For years European economies had been lagging dismally behind America (to say nothing of Asia)， but in 2006 the large continental economies had one of their best years for a decade， briefly outstripping America in terms of growth. Since politics often reacts to economic change with a lag， 2006’s improvement in economic growth will have its impact in 2007， though the recovery may be ebbing by then. C. The coming year also marks a particular point in a political cycle so regular that it almost seems to amount to a natural law. Every four or five years，European countries take a large stride towards further integration by signing a new treaty： the Maastricht treaty in 1992， the Treaty of Amsterdam in 1997， the Treaty of Nice in 2001. And in 2005 they were supposed to ratify a European constitution，laying the ground for yet more integration—until the calm rhythm was rudely shattered by French and Dutch voters. But the political impetus to sign something every four or five years has only been interrupted， not immobilised， by this setback. D. In 2007 the European Union marks the 50th anniversary of another treaty —the Treaty of Rome， its founding charter. Government leaders have already agreed to celebrate it ceremoniously， restating their commitment to “ever closer union”and the basic ideals of European unity. By itself， and in normal circumstances，the EU’s 50th-birthday greeting to itself would be fairly meaningless， a routine expression of European good fellowship. But it does not take a Machiavelli to spot that once governments have signed the declaration (and it seems unlikely anyone would be so uncollegiate as to veto it) they will already be halfway towards committing themselves to a new treaty. All that will be necessary will be to incorporate the 50th-anniversary declaration into a new treaty containing a number of institutional

(完整版)雅思考试全题模拟试题(1)

雅思考试全题模拟试题(1) Listening TIME ALLOWED: 30 minutes NUMBER OF QUESTION: 40 Instruction You will hear a number of different recordings and you will have to answer questions on what you hear. There will be time for you to read the instructions and questions, and you will have a chance to check you work. All the recordings will be played ONCE only. The test is in four sections. Write your answers in the listening question booklet. At the end of the test you will be given ten minutes to transfer your answers to an answer sheet. Now turn to Section 1 on page 2. SECTION 1 Question1-9 Question 1-6 Listen to conversation between friend and the housing officer and complete the list below. Write NO MORE THAN THREE WORDS OR NUMBERS for each answer. HOUSING LIST HOUSING LIST Address Number of rooms Price per week Additional information Mr. J Devenport 82Salisbury Road Brighton BN 16 3 AN Tel 01273 884673 2 bedrooms sitting room kit. bath Example ￡120 Unfurnished Mrs E.S. Jarvis2Wicken Street Brighton BN 15 4JH Tel 01273 771621 (1) sitting room kit.bath (2) First floor Mrs. E.C. Sparshott 180Silwood Road Brighton BN 14 9RY Tel (3) 2 large rm/s shared kit and bath ￡35 Nice area (4) Mr A Nasiry 164 Preston Road Brighton BN5 7RT Tel 01273 703865 large bedroom sitting room with kitchenette.bath. (5) Ground floor Central (6) 2 harrow Road Brighton BN9 9HK Tel 01273 745621 2 large rooms kit bath ￡86 No pets Questions 7-9 Write NO MORE THAN THREE WORDS for each answer 7.When is the accommodation available? 8.Where is the telephone? 9.How is the flat heated? SECTION 2 Questions 10-20