甲巯咪唑与丙硫氧嘧啶联合131I治疗Graves病疗效对比

甲巯咪唑与丙硫氧嘧啶联合131I治疗Graves病疗效对比张晓

【期刊名称】《中外健康文摘》

【年(卷),期】2013(000)004

【摘要】目的分析甲巯咪唑(MMI)与丙硫氧嘧啶(PTU)在131I治疗Graves病中的影响.方法360例Graves病患者中,120例仅选择131I治疗为对照(N)组,经过甲巯咪唑治疗的120例患者(A组),经过丙硫氧嘧啶治疗的120例(B组)；三组患者131I治疗剂量均按甲状腺重量给予2.59Mbq/g,六个月后比较三组疗效,甲减发生率.结果360例Graves病患者131I总有效率为98.9%,N组治愈率85.8%,A组治愈率88.3%,B组治愈率70.0%,AB两组差异有统计学意义(p<0.01).结论丙硫氧嘧啶可直接影响131I治疗Graves病的近期疗效.%Objective analysis of thiamazole and propylthiouracil in effects of 131I treatment of Graves disease. Method 360 cases Graves disease patients in the, 120 cases only select 131I treatment for controlled (n) group, after methyl-sh MI effect treatment of 120 cases patients (a, group), after c sulfur oxygen pyrimidine treatment of 120 cases (b group); three group patients 131I treatment dose are by thyroid weight giving 2.59Mbq/g, six months Hou comparison three group effect, methyl reduction occurs rate. Results of 360 patients with Graves disease 131I total effective rate of cure rates the cure rate for the 98.9%,N group 85.8%,A group88.3%,B group the cure rate 70.0%,AB two groups differences are statistically significant(p<0.01). Conclusion