Alfuzosin to relieve ureteral stent discomfort a prospective, randomized, placebo controlled study.

Alfuzosin to relieve ureteral stent discomfort: a prospective, randomized, placebo controlled study.

Beddingfield R, Pedro RN, Hinck B, Kreidberg C, Feia K, Monga M. J Urol. 2009 Jan;181(1):170-6. (PubMed Link)

This randomized, placebo controlled trial assessed the usefulness of Alfuzosin (Uroxatrol) to control stent related symptoms after ur eteroscopy. Patients were asked to complete the validated “Ureteral Stent Symptom Questionnaire” before and 3 days after ureteroscopy. Although the patients in the Alfuzosin arm reported less kidney pain during sleep, less frequent use of painkillers for kidney pain, and less interference with life from the kidney pain, the overall amount of narcotics used per day was no different.

A previous study using tamsulosin showed improvement in the “Ureteral Stent Symptom Questionnaire” and Qol scores.A comparison between the two medications might prove useful, as the autonomic effects of the two medications are different as evidenced by the different rates of ejaculatory dysfunction in a prior study.

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