2型糖尿病应用利拉鲁肽与格列美脲联合二甲双胍治疗的效果分析

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2型糖尿病应用利拉鲁肽与格列美脲联合二甲双胍治疗的效果分析

作者：刘洋王雪鹰赵锦

来源：《中外医疗》2015年第05期

[摘要] 目的探讨2型糖尿病（T2DM）应用利拉鲁肽与格列美脲联合二甲双胍治疗的效果。方法资料随机选取该院2013年9月—2014年9月收治的2型糖尿病患者98例，随机分为两组，对照组予格列美脲联合二甲双胍，观察组予利拉鲁肽联合二甲双胍，比较两组疗效、治疗前后血糖相关指标及不良反应。结果观察组总有效率83.67%略低于对照组85.71%，且

不良反应略高于对照组（P>0.05）；观察组FPG、BMI较对照组显著降低（P

[关键词] 2型糖尿病；利拉鲁肽；格列美脲；二甲双胍

[中图分类号] R587.1 [文献标识码] A [文章编号] 1674-0742（2015）02（b）-0113-02

Efficacy of type 2 diabetes with liraglutide application glimepiride metformin therapy

LIU Yang1 WANG Xueying2 ZHAO Jin3

Jinzhou city central hospital endocrinology zip code，121000 China

[Abstract] Objective Observe the effect of type 2 diabetes mellitus（T2DM） application liraglutide and glimepiride metformin therapy. Methods Data were randomly selected patients with type 2 diabetes in our hospital in September 2013-2014 September 98 treated patients were randomly divided into two groups， a control group was treated with glimepiride metformin， liraglutide group were observed with metformin， more two groups， before and after treatment and adverse reactions related indicators of blood glucose. Results Observation group total efficiency 83.67% 85.71% was slightly lower than in the control group， and the adverse reaction is slightly higher than （P>

0.05）； observation group FPG， BMI was significantly lower than the control group（P

[Key words] Type 2 diabetes； Liraglutide； Glimepiride； Metformin

临床治疗2型糖尿病（T2DM）常用的降糖药物具有增加体质重的作用，极易导致低血糖的发生，从而影响临床疗效[1-2]。为有效提高药物依从性，降低低血糖的风险，该研究针对2013年9月—2014年9月收治的98例T2DM分别给予不同药物联合方案的效果分析，旨在为临床日后选择合理的用药方案提供循证依据，现报道如下。

1 资料与方法