Creatinine_60-27-5_DataSheet_MedChemExpress

Product Name:

Creatinine CAS No.:

60-27-5Cat. No.:

HY-B0504Product Data Sheet

MWt:

113.12Formula:

C4H7N3O Purity :>98%

Solubility:

DMSO <1 mg/mL; Water 23 mg/mL

Mechanisms:

Biological Activity:

Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle, and is usually

Pathways:Others; Target:Others ()p p p ,y

produced at a fairly constant rate by the body.

Target: Others Creatinine is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass). Creatine is synthesized primarily in the liver from the methylation of glycocyamine (guanidino acetate, synthesized in the kidney from the amino acids arginine and glycine) by S-adenosyl methionine. It is then transported through blood to the other organs, muscle, and brain, where, through phosphorylation, it becomes the high-energy compound phosphocreatine. During the reaction, creatine and phosphocreatine are catalyzed by ti ki d t i t ti i [1]C ti i l l i References:

[1]. Allen, P.J., Creatine metabolism and psychiatric disorders: Does creatine supplementation have

therapeutic value. Neurosci Biobehav Rev, 2012. 36(5): p. 1442-62.[2]Levey A S et al Using standardized serum creatinine values in the modification of diet in renal creatine kinase, and a spontaneous conversion to creatinine may occur [1]. Creatinine levels in blood and urine may be used to calculate the...

[2]. Levey, A.S., et al., Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate. Ann Intern Med, 2006. 145(4): p.

247-54.Caution: Not fully tested. For research purposes only

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