超高分辨率CT(1024×1024大矩阵)在诊断肺部局灶性混杂磨玻璃影中的价值

? 1676?吉林医学2017年9月第38卷第9期

itive breast cancer [J]. Breast Cancer Res Treat, 2010,119 ( 3 )：643.

[7] Servitja S, Nogues X，Prieto -Alhambra D，et al. Bone health in a prospective cohort of postmenopausal women receiving aromatase inhibitors for early breast cancer [ J ] . Breast, 2011,21 (1):95.

[8 ] Shapiro CL, Halabi S, Gibson G. Effect of zoledronic acid (ZA) on bone mineral density ( BMD) in premenopausalwomen who develop ovarian failure ( OF) due to adjuvant chemotherapy (AdC) ：frist results from CALGB trial [J]. J Clin Oncol ,2008 ,26 (Suppl 20) ：512.

[9] Llombart A,Frassoldati A,Paija O. Immediate Administra-tion of Zoledronic Acid Reduces Aromatase Inhibitor - Associated Bone Loss in Postmenopausal Women With Early Breast Cancer：12 - month analysis of the E - ZO - FAST trial [ J ] . Clin Breast Cancer,2012,12(l) ：40.

[10] Hines SL,Sloan JA, Atherton PJ. Zoledronic acid for treat-ment of osteopenia and osteoporosis in women with primary breast cancer undergoing adjuvant aromatase inhibitor therapy [ J ] .BREAST,2010,19(2) ：92.

[11] Hershman DL，Mcmahon DJ，Crew KD，et al. Zoledronic acid prevents bone loss in premenopausal women undergoing adju-vant chemotherapy for early - stage breast cancer [ J ]. J Clin On-col, 2008 ,26(29) ：4739.

[收稿日期:2016-11 -21编校:李晓飞]

超高分辨率CT(1024 x1024大矩阵）在诊断肺部局灶性 混杂磨玻璃影中的价值

金震滨，陆健,沈继明，朱继吾,梁宏伟（南通三院影像科，江苏南通226000)

[摘要]目的：探讨超高分辨率CT(1 024 x 1 024大矩阵）在肺部局灶性混杂磨玻璃影诊断中的应用价值。方 法：回顾性分析19例经手术病理证实的肺部病变（其中肺腺癌14例，肺炎性病变5例）的超高分辨率CT(1 024 x l 024 大矩阵）的表现,19例病例分别行常规分辨率CT和超高分辨率CT(1 024 x l 024大矩阵）的对比扫描，对比病灶内部细微结构、病灶边缘及病灶邻近结构的改变。结果:超高分辨率CT(1 024 x l 024大矩阵）扫描较常规分辨率扫描更能很好地显示病灶的细微结构。结论:肺部局灶性混杂磨玻璃影需早期发现并定性，而超高分辨率CT(1 024 x l 024大矩 阵）在此方面有较强的优势。

[关键词]肺部局灶性混杂磨玻璃影；超高分辨率CT;常规分辨率CT

Application value of ultra - high resolution CT scanning (1024 * 1024 large matrix) in diagnosis of the pulmonary focal mixed ground - glass opacity JIN Zhen- bin,LU Jian,SHEN Ji- ming,et al{Imaging De-partment,The Third People's Hospital of Nantong,Nantong226QQQ,China)

Abstract：Objective To investigate the application value of ultra - high resolution CT scanning (1 024 * 1 024 large ma-trix) in the diagnosis of the pulmonary focal mixed ground - glass opacity. Method The performances of ultra - high resolution CT scanning (1 024 * 1 024 large matrix) of 19 patients with pathologically confirmed pulmonary lesions (pulmonary adenocar-cinoma in 14 patients,pulmonary inflammatory lesion in 5 patients) were retrospectively analyzed. 19 patients underwent routine CT scanning and ultra - high resolution CT scanning (1 024 * 1 024 large matrix) respectively for a comparison, and the chan-ges in internal microscopic structures of the lesions，margins of the lesions and structures adjacent to the lesions were com-pared. Results The ultra - high resolution CT scanning ( 1024 * 1 024 large matrix) can better display the microscopic struc-tures of the lesions compared to routine CT scanning. Conclusion The pulmonary focal mixed round - glass opacity should be ear-ly detected and diagnosed, and the ultra - high resolution CT scanning (1 024 * 1 024 large matrix) has a stronger advantage in this aspect.

Key Words ：Pulmonary focal mixed round - glass opacity ；Ultra - high resolution CT ；Routine CT

近年来随着多层螺旋C T的广泛应用，尤其是大矩阵螺旋 C T扫描技术的发展，C T越来越成为胸部病变的诊断最佳手 段，或为早期诊断肺肿瘤的首选,而早期肺肿瘤常表现为肺部 局限性磨玻璃密度影，大矩阵螺旋C T扫描致肺部局限性磨玻 璃密度影（focal ground - glass opacity,fGGO)的检出率越来越多[1]，有关肺部局灶磨玻璃密度影与早期支气管肺癌,尤其是 早期细支气管肺泡癌密切相关[2< ,故而能正确认识其MSCT 征像，对提高早期肺癌的诊断符合率具有非常重要的意义。笔者在医院近几年工作中通过对19例fGGO患者的MSCT征 像进行回顾性分析，找出对诊断具有重要价值的影像学征像,