核受体信号在脂类代谢中的调控作用

核受体信号在脂类代谢中的调控作用

何彦安;雷正明

【期刊名称】《国际外科学杂志》

【年(卷),期】2010(037)007

【摘要】Nuclear receptors,the superfamily of ligand-activated transcription factors,play crucial role in the regulation of gene expression of the lipid metabolism,and are involved in many metabolic diseases,such as cholesterol gallstone disease.Recently many domestic and foreign researches on the role of nuclear receptors in the lipid metabolism,help to further elucidate the biomolecular pathogenesis of cholesterol gallstone disease and other diseases associated with the lipid metabolism.%核受体是配体依赖性转录因子超家族,对脂类代谢基因有重要的转录调控作用,与许多代谢性疾病密切相关,近年来,国内外对核受体在脂类代谢中调控作用的广泛研究,有助于进一步加深对胆固醇结石病等与脂类代谢相关疾病的发病机制认识.

【总页数】4页(487-490)

【关键词】核受体;胆汁酸;胆固醇;甘油三酯

【作者】何彦安;雷正明

【作者单位】646000,泸州,泸州医学院附属医院肝胆外科;646000,泸州,泸州医学院附属医院肝胆外科

【正文语种】中文

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