银离子藻酸盐敷料用于恶性肿瘤伤口症状管理的效果研究

C(SIP Chinese General Practice _________________________________________December 2016, Vol,19

.论著.银离子藻酸盐敷料用于恶性肿瘤伤口症状管理的效果研究

部春兰，邓红艳，席祖洋，罗徵，贺利，彭金霞

【摘要】目的通过多中心随机对照方法评价银离子藻酸盐敷料处理恶性肿瘤伤口，探讨改善伤口症状和提高

患者生活质M的效果，为临床恶性肿瘤伤口的管理提供依据。方法选择2012年9月一2015年8月在宜昌市中心人民

医院、兰州大学第二医院、湖北医药学院附属人民医院伤口治疗门诊就诊的78例恶性肿瘤伤口患者，采用随机数宇表

法分为观察组和对照组，每组各39例，伤口按照统一方法评估、清洗后，观察组采用银离子藻酸盐敷料处理，对照组

采用藻酸盐敷料处理，疗程为30 d，所有患者治疗原发疾病、加强营养和情感支持。干预前，干预后15、30 d，观察

两组患者伤口病原菌阳性率、气味分级、渗液程度及疼痛fF分，采用SF-36简易量表评价生活质量。结果干预前，

两组患者伤口病原菌阳性率比较，差异无统计学意义（P>〇.05);干预后15、30 d，观察组患者伤口病原菌阳性率较

对照组降低，差异有统计学意义（P<〇.〇5)。干预前，两组患者气味分级比较，差异无统计学意义（P>0.05);干预

后15、30 d，两组患者气味分级比较，差异有统计学意义（^<0.05)。干预前、干预后15 d，两组患者渗液程度比

较，差异无统计学意义（P>〇.〇5);干预后30d，两组患者渗液程度比较，差异有统计学意义（^<0.05)6干预前，

两组患者疼痛评分比较，差异无统计学意义>〇.〇5);干预后15、30 d，观察组患者疼痛评分较对照组降低，差异

有统计学意义（P<〇.〇5h干预前，两组患者S F-36简易量表各维度评分比较，差异无统计学意义（^>0.05);干

预后15、30 d，观察组患者S F-36简易量表各维度评分较对照组升高，差异有统计学意义（P< 0.05 )。结论银离

子藻酸盐敷料和藻酸盐敷料均能改善恶性肿瘤患者伤口症状，提高患者生活质纛，但银离子藻酸盐敷料在控制伤口感

染、减轻伤口气味和疼痛、提高患者生活质量方面的效果更好。

【关键词】癌；恶性肿瘤伤口；藻酸盐；敷料；生活质量

【中图分类号】R 473. 73【文献标识码】A

Efficacy of Alginate Dressing Including Silver Ions for Malignant Tumor Wound Symptom Management GUO Chun -

lan,DENG Hong- yan,XI Zu- yang,et al.Wound Therapy Clinic of Central People's Hospital of Yichang,the Frist Clinical Medical College of China Three Gorges University,Yichang443003 ,China

[Abstract]Objective Through multi - center randomized evaluation of alginate dressing including silver ions treatment malignant tumor wound,to investigate the clinical efficacy of improve the symptoms and quality of life,provide the basis for clinical malignant tumor of wound management.Methods 78 cases of malignant tumor wound in Wound Therapy Clinic

of Central People’s Hospital of Yichang,Lanzhou University Second Hospital,People's Hospital Affiliated to Hubei Univesity of Medicine form September 2012 to August 2015 were collected,these patients were divided into observation group and control group according to the random number table,39 cases in each group,wound in accordance with the unified evaluation method,

after cleaning,cases in the observation group were treated with alginate dressing including silver ions and control group were treated with alginate dressing,the course of treatment was 30 d,treatment and observation of treatment for 30 days,all the patients treated primary disease,nutrition support and emotional support.Before the intervention,15 d and 30 d after the intervention,the wound pathogen positive rate,odor classification,infiltration degree,pain score were observed,and quality of

life were evaluated by SF- 36 simple scale.Results Before the intervention,the difference of wound pathogen positive rate between two groups was not statistically significant(P > 0.05 ) ；15 d and 30 d after the intervention,the wound pathogen positive rate in observation group was lower than that in control group,the differences were statistically significant(P< 0.05).

基金项目：宜昌市卫生科技项目（A14301 -07)

作片艰位：443003湖北省丨I丨屮心人民㈨院?三峡大7:笫一临床医学院伤丨丨治疗门诊（郭春兰），护理部（.邓红艳），人事科

(席机洋），门诊部（罗薇）；兰州大学第二医院伤口辦中心C贺莉）；湖北K药7院附虹人院伤丨丨治疗门诊（彭金谥）通信作荇?.邓红艳，443003湖北省宜昌市中心人旧欠院*三峡大7第一临床丨力7:院护观部；E-mail: 1160279690@https://www.wendangku.net/doc/8513291287.html,